Research priorities

7 MAJOR AREAS OF RESEARCH

recherche-dermo-cosmetique3.jpgProviding a comprehensive response

Eager to provide the most comprehensive cosmetological solutions possible, from assisting with skin problems to caring for the skin and hair on a daily basis, our dermo-cosmetic R&D teams focus on 7 research priority areas: hydration, skin reactivity, hyper-pigmentation, slimming, and hair biology. For each field our specialists identify attractive active substances and new pharmacological targets. They develop knowledge and appropriate methodologies to better understand the physiology of normal or diseased skin. They develop new methods for studying and evaluating product performance and safety.

The results of this research are presented during scientific congresses and published in peer-reviewed publications.

HYDRATION

hydratation.jpgIdentifying new active substances

Research into the barrier function aims to identify and qualify new active substances that act on dry skin, reinforce the barrier function, maintain epidermal homeostasis, resist stress, protect against external pathogens, repair cells, and regenerate tissue. It also covers chemical synthesis and bio-guiding of original molecules.

SKIN REACTIVITY

inflammation.jpgControlling excess skin reactions

We look for suitable active substances to control non-specific excess reactions on the skin and its appendages in types of inflammatory dermatosis such as acne, atopic dermatitis, rosacea or seborrheic dermatitis. We try to characterize the constitutional and environmental factors involved in the etiology of inflammatory dermatitis.





Numerous models have been developed by our researchers to characterize different phases of dermatosis, to study their progression, and to evaluate the pharmacodynamic activity of molecules or plant extracts that are likely to improve the condition of the skin.

PIGMENTATION

Innovative solutions to prevent and reduce pigmentation

Our research aims to provide new active substances that can brighten or homogenize the color or prevent the appearance of pigment spots such as melasma or lentigo. Clinical biology studies enable us to assess pigmentation using imaging or molecular biology techniques, in order to better understand the mechanisms involved (pigment spots, constitutive or photo-induced pigmentation). Cell or tissue models using melanocytes and keratinocytes are also developed to characterize the ways of regulating pigmentation. All these studies make it possible to offer innovative solutions for depigmentation products.

SLIMMING

minceur.jpgIncreasing the efficacy of slimming products

Our research involves identifying pharmacological targets and active substances that make it possible to increase the efficacy of slimming products.

Our laboratories working on cell, tissue and clinical pharmacology make it possible to construct original models that help evaluate the properties of active substances selected for their innovative character. Our research currently focuses on chronobiology.

HAIR BIOLOGY

cheveu.jpgThe beauty and biology of the hair and scalp

The biophysical and biomechanical properties of the hair (shine, color, flexibility, resistance, density and thickness) are studied with the help of various technologies (imaging, mechanical and optical tests on dressings) and assessed via sensory analysis. These methods make it possible to evaluate the efficacy of active substances and guide the pharmaceutical development of our hair care products.



The cell and molecular mechanisms that contribute to regulating the hair cycle, seborrhea, hydration and scalp sensitivity are studied in order to improve the management of different types of hair loss and other disorders associated with the scalp. In vitro development models based on hair bulb cell cultures, entire hair follicles and skin cells enable the selection of active substances whose in vivo efficacy is confirmed by clinical tests.