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26 INTEGRATED ANNUAL REPORT 2021 - PIERRE FABRE Prioritizing innovation Innovation at Pierre Fabre takes many forms but always abides by a core principle, namely using the “combine the best of medical and naturalness, for the good of people.” In light of this positioning, in 2020 the Group redefined its innovation strategy for Medical Care and continued its Conscious Care approach for dermo-cosmetics. Three priority areas for innovation Our innovation strategy is based on three priority areas: focusing our internal oncology research on immune therapy and new targeted therapies; establishing partnerships with biotechs and innovative research institutes to develop new treatments for niche oncology indications and rare dermatological conditions; and making “Conscious Care” the compass of our dermo-cosmetics R&D. Natural eco-friendly products Plant-based innovation forms the very heart of the Group. Since it was created, Pierre Fabre has created and marketed hundreds of products made from natural active ingredients. This includes not only medicines - such as Permixon whose active ingredient comes from the dwarf palm, but also dermo-cosmetics brands and Naturactive which specializes in plant therapy and aromatherapy. In 2020, the Group remained true to form, with for example the launch of Cleanance Comedomed by Eau Thermale Avène brand. Containing a cutting-edge active ingredient extracted from milk thistle, ComedoclastinTM, this product has been highly successful, with a million units sold around the world. Designed for acne-prone skin, this product extends the Cleanance range. In line with the Green Mission concept, the Group has set itself the goal of ensuring at least half of the products in its catalog have an eco-friendly socially- responsible design by 2023.