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36 INTEGRATED ANNUAL REPORT 2021 - PIERRE FABRE 1. Prevention Prevention thanks to extensive awareness campaigns in effective sun protection. We have a comprehensive portfolio of products designed to protect skin and keep it healthy. For example, we offer high SPF protection for all types of skin, from the most delicate (infants, children etc.), to atopic skin and people at risk of actinic keratosis. 2. Treat Treatment with medicines that target precancerous skin lesions and tumors, as well as dermo-cosmetics and oral care products that relieve the side effects of cancer treatments. 3. Support Support through a variety of tools to educate, inform and assist patients and health care professionals throughout the care pathway, from diagnosis to treatment, and beyond. A global approach to health care: the example of oncology For oncology in particular, Pierre Fabre has a unique selling point, namely its presence at every stage of the patient care pathway for prevention, treatment, and support. TRIASORBTM: the solar revolution After 20 years of research, Pierre Fabre has become the second cosmetics manufacturer in the world to launch a solar filter designed using proprietary research. TriasorbTM is the first organic filter with the unique ability to absorb and reflect the harmful portion of the solar spectrum, including UVB, shortwave UVA, longwave UVA as well as high-energy visible blue light. TriasorbTM has also undergone several tests in experimental conditions to prove a lack of toxicity for three key species for marine biodiversity. A promising beacon of hope for melanoma This particularly innovative targeted therapy combines two new generation molecules. It is designed for patients with BRAF+ melanoma, the most common type of metastatic skin cancer. Fruit of a strategic partnership forged in 2015 between Pierre Fabre and Array BioPharma, which was purchased by Pfizer in 2019, Pierre Fabre has launched this treatment in 20 European countries as well as in Australia which has one of the highest incidences of melanoma in the world. Pierre Fabre owns the marketing licenses for every country except North America and Japan. TAVIE SKIN: an app specifically designed for patients with metastatic melanoma Launched in 2020, TAVIE Skin is an app designed to inform and support patients with metastatic melanoma throughout their illness. This digital tool was developed in close partnership with health care professionals and patient associations. TAVIE Skin acts as a virtual nurse offering information about the condition, advice on treatment compliance, and support tools (appointment calendar, treatment tracking with notifications, diary, etc.) It will also be a valuable source of real-world data.