From nature to skin

100% integrated R&D.

R&D dermo-cosmetics at Pierre Fabre
Inventor of dermo-cosmetics over 50 years ago, we create and develop dermo-cosmetic care products with high added value, acting to simultaneously promote the health and beauty of the skin and hair.

R&D expertise since 1974

The Pierre Fabre Group is simultaneously a botanist, a grower and a manufacturer for its brands (like Eau Thermale Avène and Klorane).

This original position within the cosmetics industry means that we can control the product life cycle, from the plant to the skin and the hair.

With 6 research centres in France and more than 300 dermo-cosmetic research experts, the Group identifies new targets, develops new natural extracts and designs new textures.

Dermo-cosmetic R&D figures


clinical studies each year to guarantee the safety, efficacy, and sensory appeal of our formulas


ingredients removed from our raw materials catalog to get to the essentials


of new product developments since 2019 have specifications that incorporate the concept of eco-socio-design


In 2025, all our new formulas will be designed using over 90%* natural-origin ingredients *excluding sun protection products


In 2025, 100% of our packaging materials will be recyclable


of our raw materials, in 2022, were manufactured in Europe, of which 30 % in France

Knowledge of the skin, hair and plants

expert de la peau Pierre Fabre

Expert in skin care since 1974

The first Pierre Fabre research team to focus jointly on cosmetics and dermatology was created in Castres in 1974.

It then began to conduct studies on skin physiology. It rapidly accumulated knowledge and became an expert in the epidermis, with special emphasis on sun protection, skin ageing and the microbiome.  

In-depth knowledge, which in 2018 was the subject of more than 30 scientific publications in peer-reviewed journals.


Close up on hair - Pierre Fabre expertise and knowledge about hair

Knowledge of the hair

The Pierre Fabre Group's hair research centres on two approaches:

  • hair beauty: shine, color, bounce, strength, density and thickness, and
  • hair and scalp biology: the hair cycle, seborrhea, hydration and scalp sensitivity.

Our teams develop innovations for hair care products in our dermo-cosmetic brands like Klorane.

Research on plants at Pierre Fabre

Knowledge of nature

We see nature as an inexhaustible source of inspiration.

The Pierre Fabre Group researchers look to nature to find solutions for the needs of healthy and damaged skin and hair.

They select new active ingredients (29 natural-origin key ingredients in 2018) to constantly offer new dermo-cosmetic products derived from our plant heritage and biotechnologies.

Pierre Fabre, the company founder, was passionate about plants and convinced of the unlimited potential of nature.

The legacy of this passion still inspires the Group's botanists and researchers. It is also this legacy which led the company to put in place a rigorous, certified approach which bears the name Botanical Expertise Pierre Fabre (BEPF) in order to extract innovative, safe active ingredients while preserving nature and respecting suppliers.

The mastery of dermo-cosmetics

The Pierre Fabre Group has developed a knowledge and expertise chain which lets us control all the steps involved in the product design of our dermo-cosmetic brands.

Our end-to-end dermo-cosmetic design process revolves around four combined skills to guarantee the reliability and effectiveness of our products:

  • The identification of plant-based and biotechnological active ingredients
  • Formulation
  • Packaging
  • Efficacy and safety tests
Pierre Fabre art of creating new dermocosmetics formulas

The art of formulation

Day after day, our cosmetic formulation experts continuously improve the formulas of our brands and design evermore original textures (around 150 formulas in 2018).

Their job: to blend ingredients while revealing and preserving the power of the active ingredients selected.

The Pierre Fabre experts use a maximum number of natural ingredients in the products and design biodegradable formulas for rinse-off products. The following products are created in this way: emulsions, foaming products, lotions, sticks, powders, soaps, oils and more...

packaging innovation in dermocosmectics by Pierre Fabre

Packaging: the example of sterile cosmetics

In 2009, after more than 10 years of research and development, Pierre Fabre group perfected the D.E.F.I (Device for Exclusive Formula Integrity) packaging innovation for sterile cosmetics.

D.E.F.I is the first patented closure system that protects sterile formulas from all microorganisms. A packaging innovation still commended in 2018 with the award of 2 packaging Oscars.

Hotel Dieu Toulouse

Testing to guarantee product quality

Last essential step before each launch, biologists, toxicologists, clinicians and dermatologists will test the product and in particular check its safety and effectiveness

Our development process is based on a pharmaceutical culture and our dermo-cosmetic products are not exempt from the fundamental rules of medical and pharmaceutical rigour which require that nothing is claimed without having been proven.

To assess that all our dermo-cosmetic formulas are safe, we perform particularly stringent tests, beyond what is required by European legislation:

  • In vitro pre-clinical tests
  • In vivo clinical tolerance tests

Every year, more than 1,000 tests and clinical studies are conducted in humans.

Innovation Centres: diversity, a source of innovation

Since 2014, the Pierre Fabre Group has invested in the creation of regional centres for the innovation and development of dermo-cosmetic products.

These sites, which are strategic for the Group, pursue a triple mission:

  • To develop a better understanding of Asian and Brazilian skin and the local needs of consumers,
  • To recognise trends in these cosmetic markets, to develop new markets, and finally
  • To develop products that are adapted to these markets for dermo-cosmetic brands.


Innovating in Asia

trois chercheurs dans un labo d'un centre d'innovation Chine

Pierre Fabre China Innovation Center (CIC)

On June 9, 2023, Pierre Fabre inaugurated its China Innovation Center (CIC) in Shanghai, Pudong, strengthening its presence in Asia. This center detects local trends and develops product innovations for the Eau Thermale Avène, Klorane and René Furterer brands, meeting the specific needs of Asian consumers.

centre innovation bresil pierre fabre

Innovating in Latin America 

In 2018, Pierre Fabre Dermo-Cosmetics established an innovation centre in Brazil, at the heart of one of the most innovative beauty markets.

An ideal location which allows research teams to work in close proximity to local needs while collaborating with France and Japan.   

We take care of life by designing and developing innovative solutions inspired by consumers and patients, and contributing to the well-being of everyone from health to beauty.