Part 3

Financial results 2023

The company generated net sales of €2,827M in 2023. On a constant exchange rate basis, that is a 5.9% increase, driven by the two-figure growth of Eau Thermale Avène, Innovative Oncology and Medical Dermatology. The Operating Profit stood at €286M, up 12% compared to the previous financial year.

70%

of net sales were international

A stronger international presence

with our main subsidiaries based in China, Germany, Spain and Italy accounting for a cumulated revenue of more than €700M. Our 5 other priority regions — the US, Mexico, Brazil, Benelux and Poland — achieved a growth of 17%. Our objective of generating over €500M by 2025.

Répartition du CA par zone géographique
Breakdown of net sales by region

38 % Europe (excluding France)

31 % France

14 % Asia- Pacific

11 % Americas

6 % Africa/Middle East/Turkey

Breakdown of net sales by activity

57 % Dermo-Cosmetics & Personal Care

19 % other drugs

16 % Oncology

7 % Medical dermatology

1 % Other activities/areas

Répartition du CA par activité

High-growth activities

Dermo-Cosmetics & Personal Care (DC&PC) generated net sales of €1,60M, 57% of total revenue, a 9.9% growth on a constant scope and exchange rate basis.

Eau Thermale Avène obtained revenue above the symbolic €1bn threshold, reaffirming its ranking as the world’s No. 2 dermo-cosmetics brand. Ducray, A-Derma, Darrow and Pierre Fabre Oral Care also posted significant growth.

Medical Care generated net sales of €1,174 million, 42% of the company’s total revenue, up 4% compared to 2022 on a constant scope and exchange rate basis.

The growth of Innovative Oncology was driven by three targeted therapies for the treatment of cancers with specific mutations (melanoma, colorectal cancer and breast cancer). This past year also marked the launch of the world's first allogeneic T-cell immunotherapy available in Europe, for the treatment of a rare lymphoproliferative disorder.

+12 %

increase in the R&D budget

200 M€

in acquisitions

Innovation as a driving force

We have invested heavily in innovation. On the one hand, our research and development budget rose by 12% to €190M. On the other, we signed several partnerships and/or acquisitions for a total investment of more than €200M

Partnership with Scorpion Therapeutics for the co-development of active ingredients STX-721 and STX-241 and the acquisition of a license to market them in Europe and China (treatment for non- small cell lung cancer).

Acquisition of Vertical Bio and its drug candidate VERT- 002 (e.g., of non-small cell lung cancer).

Expansion of licensing rights for EBVALLO® (tabelecleucel) to all territories worldwide (treatment of a rare lymphoproliferative disorder).

Acquisition of MÊME Cosmetics, the first-ever brand of dermo-cosmetic care products to alleviate the adverse effects of cancer treatments.

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